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historically, the small numbers of children presenting with gender dysphoria were primarily prepubescent males. in recent years, there has been a sharp increase in referrals of adolescents, and particularly adolescent females, to gender clinics. many do not have a significant history of childhood gender dysphoria and a number suffer from comorbid mental health issues and neurodevelopmental conditions such as autism (asd) and attention-deficit/hyperactivity disorder (adhd). the reasons for these changes are understudied and remain poorly understood. childhood-onset gender dysphoria has been shown to have a high rate of natural resolution, with 61-98% of children reidentifying with their biological *** during puberty. the research into the course of gender dysphoria desistance among the cohort presenting with adolescent-onset gender dysphoria is still in its infancy, due to the novelty of this presentation. however, recent research from the uk clinic population suggests that 10-12% of youth may be detransitioning within 16 months to 5 years of initiating medical interventions, with an additional 20-22% discontinuing treatments for a range of reasons. the researchers noted that the detransition rate found in the recently-presenting population raises critical questions about the phenomenon of "overdiagnosis, overtreatment, or iatrogenic harm as found in other medical fields."
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Cymbalta (duloxetine) is a *** used to treat anxiety, major depressive disorder, and chronic pain related to certain health conditions ..
