cavallilab.org Cavallilab.org

   
Computational Biology and Integrative Genomics of *** - Institut Curie

Domain Summary

What IP addresses does Cavallilab.org resolve to?

• Cavallilab.org resolves to the IP addresses 46.30.215.127.

Where are Cavallilab.org servers located in?

• Cavallilab.org has servers located in Copenhagen, Capital Region, 1510, Denmark.

cavallilab.org Profile

Title:Computational Biology and Integrative Genomics of *** - Institut Curie Description:Transcriptional deregulation is a critical aspect of *** biology, that affects tumor initiation, maintenance, response to treatment, and recurrence. Indeed, the transcriptional program responsible for development and cell type diversity is also responsible for *** cell states.Spontaneous applications for dry-lab project are welcomed, a minimum of bioinformatics/data analysis skills is asked. Please email florence.cavalli@curie.fr.This program is controlled by master transcriptional regulators that drive genes’ transcriptional output. We study transcriptional (de)regulation and *** master transcriptional regulators in two major contexts: (i) temporal heterogeneity specifically in the setting of recurrent disease and (ii) intra-tumoral heterogeneity. These types of heterogeneity are of critical clinical importance since they represent two major causes of treatment failure. The few studies performed on treatment resistant recurrences showed that they are highly genetically different from the matched untreated diagnostic samples. In addition, intra-tumoral heterogeneity studies focused on genetic events have shown significant geographical heterogeneity across several tumor types. However, despite the identification of genetic and epigenetic events with spatial and temporal disparity, the heterogeneity at the level of master regulators, that drive *** from ontogeny through to oncogenesis is unknown and the specific driver pathways resulting in treatment resistance have proved elusive. An improved understanding of the transcriptional program and especially of the master regulators driving the ***-specific programs is therefore of critical importance. In order to decipher mechanisms of resistance, we focus on the master regulators that drive transcriptional output. An understanding of the temporal changes in transcriptional programs is a powerful tool to understand tumor evolution and treatment resistance. We analyse and perform integrative studies of NGS data, single-cell data, and clinical information from patient samples to increase our understanding of tumor heterogeneity and resistance to treatment, especially in high-grade gliomas.

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Where is cavallilab.org hosted?

Cavallilab.org may be hosted in multiple data centers distributed in different locations around the world. This is probably just one of them.
Server IP:
46.30.215.127
ASN:
AS51468 
ISP:
One.com A/S 
Server Location:
Copenhagen
Capital Region, 84
1510
Denmark, DK
 

Other sites hosted on 46.30.215.127

There are no other sites hosted on this IP

How fast does cavallilab.org load?

The average loading time of cavallilab.org is 336 ms. The Desktop speed index is 0 and mobile speed index is 55.
Average Load Time:
336 ms

Page Speed (Google PageSpeed Insights) - Mobile

55
0-49 50-89 90-100 i

Field Data

Over the last 30 days, the field data shows that this page has a AVERAGE speed compared to other pages in the Chrome User Experience Report.We are showing the 90th percentile of FCP and the 95th percentile of FID.

Cumulative Layout Shift (CLS)15ms 0% of loads for this page have a fast (<0.01s) Cumulative Layout Shift (CLS) 67% 18% of loads for this page have an average (0.01s ~ 0.025s) Cumulative Layout Shift (CLS) 18% 14% of loads for this page have a slow (>0.025s) Cumulative Layout Shift (CLS) 14%
Time To First Byte (TTFB)1.2s 0% of loads for this page have a fast (<800s) Time To First Byte (TTFB) 52% 37% of loads for this page have an average (800s ~ 1800s) Time To First Byte (TTFB) 37% 10% of loads for this page have a slow (>1800s) Time To First Byte (TTFB) 10%
First Contentful Paint (FCP)2.3s 0% of loads for this page have a fast (<1.8s) First Contentful Paint (FCP) 65% 18% of loads for this page have an average (1.8s ~ 3s) First Contentful Paint (FCP) 18% 16% of loads for this page have a slow (>3s) First Contentful Paint (FCP) 16%
First Input Delay (FID)0 0% of loads for this page have a fast (<0ms) First Input Delay (FID) 0% 0% of loads for this page have an average (0ms ~ 0ms) First Input Delay (FID) 0% 0% of loads for this page have a slow (>0ms) First Input Delay (FID) 0%
Interactive To Next Paint (INP)170ms 0% of loads for this page have a fast (<200s) Interactive To Next Paint (INP) 81% 16% of loads for this page have an average (200s ~ 500s) Interactive To Next Paint (INP) 16% 1% of loads for this page have a slow (>500s) Interactive To Next Paint (INP) 1%
Largest Contentful Paint (LCP)2.6s 0% of loads for this page have a fast (<2500s) Largest Contentful Paint (LCP) 72% 15% of loads for this page have an average (2500s ~ 4000s) Largest Contentful Paint (LCP) 15% 11% of loads for this page have a slow (>4000s) Largest Contentful Paint (LCP) 11%

Origin Data

All pages served from this origin have an AVERAGE speed compared to other pages in the Chrome User Experience Report. over the last 30 days.To view suggestions tailored to each page, analyze individual page URLs.

Cumulative Layout Shift (CLS)15ms 67% of loads for this page have a fast (<0.01s) Cumulative Layout Shift (CLS) 67% 18% of loads for this page have an average (0.01s ~ 0.025s) Cumulative Layout Shift (CLS) 18% 14% of loads for this page have a slow (>0.025s) Cumulative Layout Shift (CLS) 14%
Time To First Byte (TTFB)1.2s 52% of loads for this page have a fast (<0.8s) Time To First Byte (TTFB) 52% 37% of loads for this page have an average (0.8s ~ 1.8s) Time To First Byte (TTFB) 37% 10% of loads for this page have a slow (>1.8s) Time To First Byte (TTFB) 10%
First Contentful Paint (FCP)2.3s 65% of loads for this page have a fast (<1.8s) First Contentful Paint (FCP) 65% 18% of loads for this page have an average (1.8s ~ 3s) First Contentful Paint (FCP) 18% 16% of loads for this page have a slow (>3s) First Contentful Paint (FCP) 16%
First Input Delay (FID)0 0% of loads for this page have a fast (<0ms) First Input Delay (FID) 0% 0% of loads for this page have an average 0ms ~ 0ms) First Input Delay (FID) 0% 0% of loads for this page have a slow (>0ms) First Input Delay (FID) 0%
Interactive To Next Paint (INP)170ms 81% of loads for this page have a fast (<0.2s) Interactive To Next Paint (INP) 81% 16% of loads for this page have an average (0.2s ~ 0.5s) Interactive To Next Paint (INP) 16% 1% of loads for this page have a slow (>0.5s) Interactive To Next Paint (INP) 1%
Largest Contentful Paint (LCP)2.6s 72% of loads for this page have a fast (<2.5s)Largest Contentful Paint (LCP) 72% 15% of loads for this page have an average (2.5s ~ 4s)Largest Contentful Paint (LCP) 15% 11% of loads for this page have a slow (>4s)Largest Contentful Paint (LCP) 11%

Lab Data

Speed Index 10.3 s
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Largest Contentful Paint 12.5 s
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INP breakdown  
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LCP request discovery  
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Total Blocking Time 110 ms
Sum of all time periods between FCP and Time to Interactive, when task length exceeded 50ms, expressed in milliseconds. Learn more about the Total Blocking Time metric
Max Potential First Input Delay 150 ms
The maximum potential First Input Delay that your users could experience is the duration of the longest task. Learn more about the Maximum Potential First Input Delay metric
First Contentful Paint 10.3 s
First Contentful Paint marks the time at which the first text or image is painted. Learn more about the First Contentful Paint metric
Time to Interactive 12.7 s
Time to Interactive is the amount of time it takes for the page to become fully interactive. Learn more about the Time to Interactive metric

Does cavallilab.org use compression?

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cavallilab.org use gzip compression.
Original size: 2.78 MB
Compressed size: 780.68 KB
File reduced by: 2.02 MB (72%)

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SSL Checker - SSL Certificate Verify

An SSL (Secure Sockets Layer) certificate is a digital certificate that establishes a secure encrypted connection between a web server and a user's web browser. It provides authentication and encryption, ensuring that data transmitted between the server and the browser remains private and protected. cavallilab.org supports HTTPS.
 cavallilab.org supports HTTPS
     
Verifying SSL Support. Please wait...
Common Name: institut-curie.org
Organization: INSTITUT CURIE
Location: Paris, \C3\8Ele-de-France, FR
Issuer: GEANT TLS RSA 1
Valid from: Sep 16 12:46:15 2025 GMT
Valid until: Sep 16 12:46:15 2026 GMT
Authority:
Keysize: 2048 Bits
Common Name: GEANT TLS RSA 1
Organization: Hellenic Academic and Research Institutions CA
Location: GR
Issuer: HARICA TLS RSA Root CA 2021
Valid from: Jan 3 11:15:00 2025 GMT
Valid until: Dec 31 11:14:59 2039 GMT
Authority: CA:TRUE
Keysize: 3072 Bits
Common Name: HARICA TLS RSA Root CA 2021
Organization: Hellenic Academic and Research Institutions CA
Location: GR
Issuer: Hellenic Academic and Research Institutions RootCA 2015
Valid from: Sep 2 07:41:55 2021 GMT
Valid until: Aug 31 07:41:54 2029 GMT
Authority: CA:TRUE
Keysize: 4096 Bits

Verify HTTP/2 Support

HTTP/2 (Hypertext Transfer Protocol version 2) is a major revision of the HTTP protocol, which is the foundation of data communication on the World Wide Web. It was developed as an improvement over the previous HTTP/1.1 version to enhance web performance and efficiency.
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Http Header

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cache-control: max-age:600, public
content-length: 337
expires: Thu, 29 Jan 2026 21:55:01 GMT
last-modified: Thu, 29 Jan 2026 21:45:01 GMT
location: https://science.institut-curie.org/research/integrated-biology/bioinformatics-biostatistics-epidemiology-and-computational-systems-biology-of-cancer/computational-biology-and-integrative-genomics-of-cancer/
date: Thu, 29 Jan 2026 21:45:01 GMT
content-type: text/html; charset=utf-8
x-varnish: 10910209602
age: 0
via: 1.1 webcache2 (Varnish/trunk)

HTTP/2 301 
content-length: 0
location: https://institut-curie.org/team/cavalli

HTTP/2 200 
vary: Accept-Encoding
content-type: text/html;charset=utf-8
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date: Thu, 29 Jan 2026 21:44:02 GMT
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DNS Lookup

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Type Ip Target/Txt TTL
A 46.30.215.127 3550