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1gene.com
Genentech
Breakthrough science. One moment, one day, one person at a time.

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2xolair.com
Allergic Asthma and CIU Treatment | XOLAIR® (Omalizumab)
XOLAIR® (omalizumab) is a treatment for moderate to severe persistent allergic asthma and Chronic Idiopathic Urticaria (CIU) in appropriate patients.

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3rituxan.com

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4weightloss.com
Welcome to: Weightloss.com
Welcome to: Weightloss.com

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5herceptin.com

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6activase.com
Activase® (Alteplase) for Acute Ischemic Stroke Treatment
Learn more about Activase® (Alteplase) for Acute Ischemic Stroke Treatment. Indications Activase (alteplase) is indicated for the treatment of acute ischemic stroke. Exclude intracranial *** as the primary cause of stroke signs and symptoms prior to initiation of treatment. Initiate treatment as soon as possible but within 3 hours after symptom onset. Activase is indicated for use in acute myocardial infarction (AMI) for the reduction of mortality and reduction of the incidence of heart failure. Limitation of Use: The risk of stroke may outweigh the benefit produced by thrombolytic therapy in patients whose AMI puts them at low risk for *** or heart failure. Activase is indicated for the lysis of acute massive pulmonary *** (PE), defined as: • Acute pulmonary emboli obstructing blood flow to a lobe or multiple lung segments. • Acute pulmonary emboli accompanied by unstable hemodynamics, e.g.,failure to maintain blood pressure without supportive measures. Important Safety Information Contraindications Do not administer Activase to treat acute ischemic stroke in the following situations in which the risk of bleeding is greater than the potential benefit: current intracranial *** (ICH); subarachnoid ***; active internal bleeding; recent (within 3months) intracranial or intraspinal surgery or serious head trauma; presence of intracranial conditions that may increase the risk of bleeding; bleeding diathesis; and current severe uncontrolled hypertension. Do not administer Activase to treat acute myocardial infarction or pulmonary *** in the following situations in which the risk of bleeding is greater than the potential benefit: active internal bleeding; history of recent stroke; recent (within 3months) intracranial or intraspinal surgery or serious head trauma; presence of intracranial conditions that may increase the risk of bleeding; bleeding diathesis; and current severe uncontrolled hypertension. Warnings and Precautions Bleeding Activase can cause significant, sometimes fatal, internal or external bleeding, especially at arterial and venous puncture sites.Avoid intramuscular injections and trauma to the patient. Fatal cases of *** associated with traumatic intubation in patients administered Activase have been reported. Heparin, aspirin, or Activase may cause bleeding complications; therefore carefully monitor for bleeding. If serious bleeding occurs, terminate the Activase infusion. Orolingual Angioedema Monitor patients during and for several hours after infusion for orolingual angioedema. If angioedema develops, discontinue the Activase infusion and promptly institute appropriate therapy. Cholesterol Embolization Cholesterol ***, sometimes fatal, has been reported rarely in patients treated with thrombolytic agents. Reembolization of Deep Venous Thrombi during Treatment for Acute Massive Pulmonary *** Consider the possible risk of reembolization due to the lysis of underlying deep venous thrombi patients with acute massive PE Coagulation Tests May be Unreliable during Activase Therapy Coagulation tests and/or measures of fibrinolytic activity may be unreliable during Activase therapy. Adverse Reactions The most frequent adverse reaction associated with Activase therapy is bleeding. Allergic‑type reactions, e.g.,anaphylactoid reaction, laryngeal edema, orolingual angioedema, rash, and urticaria have been reported.

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7ocrevus.com
Relapsing or Primary Progressive MS | OCREVUS™ (ocrelizumab)
Find information about OCREVUS™ (ocrelizumab), a prescription medicine used to treat relapsing multiple sclerosis (RMS), or primary progressive multiple sclerosis (PPMS). OCREVUS is a prescription medicine used to treat adults with relapsing or primary progressive forms of multiple sclerosis. What is OCREVUS? OCREVUS is a prescription medicine used to treat adults with relapsing or primary progressive forms of multiple sclerosis. It is not known if OCREVUS is safe or effective in children. Who should not receive OCREVUS? Do not receive OCREVUS if you have an active hepatitis B virus (HBV) infection. Do not receive OCREVUS if you have had a life threatening allergic reaction to OCREVUS. Tell your healthcare provider if you have had an allergic reaction to OCREVUS or any of its ingredients in the past. What is the most important information I should know about OCREVUS? OCREVUS can cause serious side effects, including: Infusion reactions: OCREVUS can cause infusion reactions that can be serious and require you to be hospitalized. You will be monitored during your infusion and for at least 1 hour after each infusion of OCREVUS for signs and symptoms of an infusion reaction. Infection: OCREVUS increases your risk of getting upper respiratory tract infections, lower respiratory tract infections, skin infections, and herpes infections. If you have an active infection, your healthcare provider should delay your treatmentwith OCREVUS until your infection is gone. What are the possible side effects of OCREVUS? OCREVUS may cause serious side effects, including: Risk of cancers (malignancies) including breast ***. Follow your healthcare provider’s instructions about standard screening guidelines for breast ***. Most common side effects include infusion reactions and infections. These are not all the possible side effects of OCREVUS. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. For more information, go to www.OCREVUS.com or call 1-844-627-3887 For additional safety information, please see the full Prescribing Information and *** Guide.

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8tecentriq.com
Treatment for mUC & NSCLC |TECENTRIQ® (atezolizumab)
Find information about TECENTRIQ® (atezolizumab) Advanced Urothelial Carcinoma (mUC) or metastatic non-small cell lung *** (NSCLC) treatment. INDICATION: TECENTRIQ is a prescription medicine used to treat a type of bladder and urinary tract *** called urothelial carcinoma. TECENTRIQ may be used when your bladder ***: has spread or cannot be removed by surgery (advanced urothelial carcinoma), and you are not able to take chemotherapy that contains a medicine called cisplatin, or you have tried chemotherapy that contains platinum, and it did not work or is no longer working. The approval of TECENTRIQ in these patients is based on a study that measured response rate and duration of response. There is an ongoing study to confirm clinical benefit. a type of lung *** called non-small cell lung *** (NSCLC). TECENTRIQ may be used when your lung ****: has spread or grown, and you have tried chemotherapy that contains platinum, and it did not work or is no longer working. * If your tumor has an abnormal EGFR or ALK gene, you should have also tried an FDA-approved therapy for tumors with these abnormal genes, and it did not work or is no longer working. It is not known if TECENTRIQ is safe and effective in children. IMPORTANT SAFETY INFORMATION: What is the most important information about TECENTRIQ? TECENTRIQ can cause your immune system to attack normal organs and tissues in many areas of your body and can affect the way they work. These problems can sometimes become serious or life threatening and can lead to ***. Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may delay or completely stop treatment with TECENTRIQ if you have severe side effects. Call or see your healthcare provider right away if you get any symptoms of the following problems or these symptoms get worse. TECENTRIQ can cause serious side effects, including: Lung problems (pneumonitis)–signs and symptoms may include new or worsening cough, shortness of breath, and chest pain, Liver problems (hepatitis)–signs and symptoms of hepatitis may include yellowing of your skin or the whites of your eyes, severe nausea or vomiting, pain on the right side of your stomach area (abdomen), drowsiness, dark urine (tea colored), bleeding or bruising more easily than normal, and feeling less hungry than usual, Intestinal problems (colitis)–signs and symptoms of colitis may include diarrhea (loose stools) or more bowel movements than usual, blood in your stools or dark, tarry, sticky stools, and severe stomach area (abdomen) pain or tenderness, Hormone gland problems (especially the pituitary, thyroid, adrenal glands, and pancreas)–signs and symptoms that your hormone glands are not working properly may include headaches that will not go away or unusual headaches, extreme tiredness, weight gain or weight loss, dizziness or fainting, feeling more hungry or thirsty than usual, hair loss, changes in mood or behavior (such as decreased *** drive, irritability, or forgetfulness), feeling cold, constipation, your voice gets deeper, urinating more often than usual, nausea or vomiting, and stomach area (abdomen) pain, Nervous system problems (neuropathy, meningitis, encephalitis)–signs and symptoms of nervous system problems may include severe muscle weakness, numbness or tingling in hands and feet, fever, confusion, changes in mood or behavior, extreme sensitivity to light, and neck stiffness, Nervous system problems (neuropathy, meningitis, encephalitis)–signs and symptoms of nervous system problems may include severe muscle weakness, numbness or tingling in hands and feet, fever, confusion, changes in mood or behavior, extreme sensitivity to light, and neck stiffness, Inflammation of the eyes–signs and symptoms may include blurry vision, double vision, or other vision problems, and eye pain or redness, Severe infections–signs and symptoms of infection may include fever, cough, frequent urination, flu-like symptoms, and pain when urinating, Severe infusion reactions–signs and symptoms of infusion reactions may include chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, fever, feeling like passing out, back or neck pain, and swelling of your face or lips. Before you receive TECENTRIQ, tell your healthcare provider about all your medical conditions, including if you: Have immune system problems (such as Crohn’s disease, ulcerative colitis, or lupus); have had an organ transplant; have lung or breathing problems; have liver problems; have a condition that affects your nervous system (such as myasthenia gravis or Guillain-Barré syndrome); or are being treated for an infection, Are pregnant or plan to become pregnant, TECENTRIQ can harm your unborn baby, If you are able to become pregnant, you should use an effective method of birth control during your treatment and for at least 5 months after the last dose of TECENTRIQ, Are breastfeeding or plan to breastfeed, It is not known if TECENTRIQ passes into your breast milk. Do not breastfeed during treatment and for at least 5 months after the last dose of TECENTRIQ. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. The most common side effects of TECENTRIQ in people with urothelial carcinoma include: Feeling tired, Decreased appetite, Nausea, Constipation, Urinary tract infection, Diarrhea, Fever. The most common side effects of TECENTRIQ in people with non-small cell lung *** include: Feeling tired, Decreased appetite, Shortness of breath, Cough, Nausea, Muscle or bone pain, Constipation. TECENTRIQ may cause fertility problems in females, which may affect the ability to have children. Talk to your healthcare provider if you have concerns about fertility. These are not all the possible side effects of TECENTRIQ. Ask your healthcare provider or pharmacist for more. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555. Please see full Prescribing Information for additional Important Safety Information.

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9avastin.com
Avastin® (bevacizumab) | Official Patient & Caregiver Website
Official *** website with information for patients and health professionals.Learn about Avastin (bevacizumab) solution for IV infusion, including benefits & risks, possible side effects, patient support, and options for financial help. Glioblastoma (GBM) Avastin is approved to treat glioblastoma (GBM) when taken alone in *** patients whose *** has progressed after prior treatment (recurrent or rGBM). The effectiveness of Avastin in rGBM is based on tumor response. Currently, no data have shown whether or not Avastin improves disease-related symptoms or survival in people with rGBM. Metastatic Colorectal *** (mCRC) Avastin is approved to treat metastatic colorectal *** (mCRC) for: First- or second-line treatment in combination with intravenous 5-fluorouracil–based chemotherapy Second-line treatment when used with fluoropyrimidine-based (combined with irinotecan or oxaliplatin) chemotherapy after *** progresses following a first-line treatment that includes Avastin Avastin is not approved for use after the primary treatment of colon *** that has not spread to other parts of the body. Non–Small Cell Lung *** (NSCLC) Avastin, in combination with carboplatin and paclitaxel, is approved to treat advanced nonsquamous non–small cell lung *** (NSCLC) in people who have not received chemotherapy for their advanced disease. Metastatic Kidney *** (mRCC) Avastin, used with interferon alfa, is approved to treat metastatic kidney *** (mRCC). POSSIBLE SERIOUS SIDE EFFECTS: Everyone reacts differently to Avastin therapy. So it's important to know what the side effects are. Although some people may have a life-threatening side effect, most do not. Your doctor will stop treatment if any serious side effects occur. Be sure to contact your health care team if there are any signs of side effects. Most serious side effects (not common, but sometimes fatal): GI perforation: A hole that develops in your stomach or intestine. Symptoms include pain in your abdomen, nausea, vomiting, constipation, or fever. Wounds that don't heal: A cut made during surgery can be slow to heal or may not fully heal. Avastin should not be used for at least 28 days before or after surgery and until surgical wounds are fully healed. Serious bleeding: This includes vomiting or coughing up blood; bleeding in the stomach, brain, or spinal cord; nosebleeds; and vaginal bleeding. If you recently coughed up blood or had serious bleeding, be sure to tell your doctor. OTHER POSSIBLE SERIOUS SIDE EFFECTS: Severe high blood pressure: Blood pressure that severely spikes or shows signs of affecting the brain. Blood pressure should be monitored every 2 to 3 weeks while on Avastin and after stopping treatment. Kidney problems: These may be caused by too much protein in the urine and can sometimes be fatal. Infusion reactions: These were uncommon with the first dose (less than 3% of patients). 0.2% of patients had severe reactions. Infusion reactions include high blood pressure or severe high blood pressure that may lead to stroke, trouble breathing, decreased oxygen in red blood cells, a serious allergic reaction, chest pain, headache, tremors, and excessive sweating. Your doctor or nurse will monitor you for signs of infusion reactions. Severe stroke or heart problems: These may include blood clots, mini-stroke, heart attack, and chest pain. These can sometimes be fatal. A passage between two organs: This type of passage\u2014known as a fistula\u2014does not form normally and can sometimes be fatal. Nervous system and vision problems: Signs include headache, seizure, high blood pressure, sluggishness, confusion, and blindness. SIDE EFFECTS SEEN MOST OFTEN: In clinical studies across different types of ***, some patients experienced the following side effects: High blood pressure, Too much protein in the urine, Nosebleeds, *** bleeding, Back pain, Headache, Taste change, Dry skin, Inflammation of the skin, Inflammation of the nose, Watery eyes. AVASTIN IS NOT FOR EVERYONE: Talk to your doctor if you are: Undergoing surgery: Avastin should not be used for 28 days before or after surgery and until surgical wounds are fully healed. Breast-feeding or pregnant: Avastin may harm a nursing child or a baby in the womb. Planning to become pregnant: Taking Avastin could cause a woman's ovaries to stop working and may impair her ability to have children. If you stop Avastin, you should keep using birth control for at least 6 months before trying to become pregnant If you have any questions about your condition or treatment, talk to your doctor. You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. Please see full Product Information, including Serious Side Effects, for additional important safety information.POSSIBLE SERIOUS SIDE EFFECTS: Everyone reacts differently to Avastin therapy. So it's important to know what the side effects are. Although some people may have a life-threatening side effect, most do not. Your doctor will stop treatment if any serious side effects occur. Be sure to contact your health care team if there are any signs of side effects. Most serious side effects (not common, but sometimes fatal): GI perforation: A hole that develops in your stomach or intestine. Symptoms include pain in your abdomen, nausea, vomiting, constipation, or fever. Wounds that don't heal: A cut made during surgery can be slow to heal or may not fully heal. Avastin should not be used for at least 28 days before or after surgery and until surgical wounds are fully healed. Serious bleeding: This includes vomiting or coughing up blood; bleeding in the stomach, brain, or spinal cord; nosebleeds; and vaginal bleeding. If you recently coughed up blood or had serious bleeding, be sure to tell your doctor. OTHER POSSIBLE SERIOUS SIDE EFFECTS: Severe high blood pressure: Blood pressure that severely spikes or shows signs of affecting the brain. Blood pressure should be monitored every 2 to 3 weeks while on Avastin and after stopping treatment. Kidney problems: These may be caused by too much protein in the urine and can sometimes be fatal. Infusion reactions: These were uncommon with the first dose (less than 3% of patients). 0.2% of patients had severe reactions. Infusion reactions include high blood pressure or severe high blood pressure that may lead to stroke, trouble breathing, decreased oxygen in red blood cells, a serious allergic reaction, chest pain, headache, tremors, and excessive sweating. Your doctor or nurse will monitor you for signs of infusion reactions. Severe stroke or heart problems: These may include blood clots, mini-stroke, heart attack, and chest pain. These can sometimes be fatal. A passage between two organs: This type of passage\u2014known as a fistula\u2014does not form normally and can sometimes be fatal. Nervous system and vision problems: Signs include headache, seizure, high blood pressure, sluggishness, confusion, and blindness. SIDE EFFECTS SEEN MOST OFTEN: In clinical studies across different types of ***, some patients experienced the following side effects: High blood pressure, Too much protein in the urine, Nosebleeds, *** bleeding, Back pain, Headache, Taste change, Dry skin, Inflammation of the skin, Inflammation of the nose, Watery eyes. AVASTIN IS NOT FOR EVERYONE: Talk to your doctor if you are: Undergoing surgery: Avastin should not be used for 28 days before or after surgery and until surgical wounds are fully healed. Breast-feeding or pregnant: Avastin may harm a nursing child or a baby in the womb. Planning to become pregnant: Taking Avastin could cause a woman's ovaries to stop working and may impair her ability to have children. If you stop Avastin, you should keep using birth control for at least 6 months before trying to become pregnant If you have any questions about your condition or treatment, talk to your doctor. You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555. Please see full Product Information, including Serious Side Effects, for additional important safety i

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10genentech-forum.com
Welcome To Genentech Forum | Managed Care Education & Support
Learn why the site of caremay impact cost in oncologyA recent Milliman actuarial analysis from 40 million commercially insured lives explored cost differences for oncology care in hospital and community settings.See More 01

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11gatherms.com
GatherMS | Nationwide (available online / by phone) | GatherMS is a place for the MS community to find and explore local services and resources for people living with MS.

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12rituxanforgpampa.com
Rituxan® (rituximab) GPA and MPA Treatment
Learn about Rituxan® (rituximab), used for Granulomatosis with Polyangiitis (formerly Wegener's Granulomatosis) and Microscopic Polyangiitis treatment. See full safety for more information.

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13msimmunology.com
Genentech: Multiple Sclerosis
Breakthrough science. One moment, one day, one person at a time.

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14thelungcancerproject.org
The Lung Cancer Project
The Lung Cancer Project aims to remove the stigma and barriers faced by people with lung cancer through awareness - so everyone receives the care they deserve.

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15genentech.com

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16lucentisdirect.com
LUCENTIS (ranibizumab injection) is now available at a new discount, only through LUCENTIS Direct TM. Celebrate 2012 with a 2.4percent discount.

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17asthmamatters.com

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18diabeteseyecheck.org
Retina Eye Exam for Preventing Vision Loss from Diabetes | Diabetes Eye Check
Learn how diabetes can lead to vision loss and what yearly retina eye exams can do to help.

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19beyondpsoriasis.com
Genentech
A patient advocacy website, sponsored by Genentech. Provides information and tips for coping with the social, workplace, relationship and self-esteem issues of psoriasis.Breakthrough science. One moment, one day, one person at a time.

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20gene.net
Genentech
Breakthrough science. One moment, one day, one person at a time.

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21biooncology.com
Genentech BioOncology Therapy Research
At Genentech BioOncology we're fundamentally transforming theway is treated, with the goal of moving therapy research towards a more manageable disease.

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22herstory.com
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